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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KDM5B All Species: 20.91
Human Site: S932 Identified Species: 46
UniProt: Q9UGL1 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UGL1 NP_006609.3 1544 175645 S932 Q A C L D P S S L T L D D M R
Chimpanzee Pan troglodytes Q5XUN4 1535 173724 R931 A L A P S A H R G S L V I M Q
Rhesus Macaque Macaca mulatta XP_001090508 1411 159177 Q847 P H R V A G L Q M T L A E L R
Dog Lupus familis XP_537122 1727 195532 S1115 Q A C L D P S S L T L D D M R
Cat Felis silvestris
Mouse Mus musculus Q80Y84 1544 175537 S932 Q A C L D S S S L S L D D M R
Rat Rattus norvegicus NP_001100647 1544 175257 S932 Q A C L D S S S L S L D D M R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508780 1538 174757 S926 Q A C L D P S S L T L D D M R
Chicken Gallus gallus Q5F3R2 1522 173443 S907 M A S A E Q N S L T L D D M R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6IQX0 1503 171080 G923 D P V A N P C G L S L E S M R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VMJ7 1838 203974 K1072 G L R E T S S K L T Y Q D V K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q23541 1477 170773 E913 E I E K I I E E G D E Y D I K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 46.5 46.3 84.7 N.A. 94.2 93.9 N.A. 89.9 82.7 N.A. 63.3 N.A. 35.2 N.A. 29.2 N.A.
Protein Similarity: 100 64.5 61.3 86.7 N.A. 96.6 96.5 N.A. 94.7 90.4 N.A. 76.4 N.A. 50.5 N.A. 49 N.A.
P-Site Identity: 100 13.3 20 100 N.A. 86.6 86.6 N.A. 100 60 N.A. 33.3 N.A. 26.6 N.A. 6.6 N.A.
P-Site Similarity: 100 26.6 46.6 100 N.A. 93.3 93.3 N.A. 100 73.3 N.A. 53.3 N.A. 40 N.A. 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 55 10 19 10 10 0 0 0 0 0 10 0 0 0 % A
% Cys: 0 0 46 0 0 0 10 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 46 0 0 0 0 10 0 55 73 0 0 % D
% Glu: 10 0 10 10 10 0 10 10 0 0 10 10 10 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 0 0 0 0 10 0 10 19 0 0 0 0 0 0 % G
% His: 0 10 0 0 0 0 10 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 0 10 10 0 0 0 0 0 0 10 10 0 % I
% Lys: 0 0 0 10 0 0 0 10 0 0 0 0 0 0 19 % K
% Leu: 0 19 0 46 0 0 10 0 73 0 82 0 0 10 0 % L
% Met: 10 0 0 0 0 0 0 0 10 0 0 0 0 73 0 % M
% Asn: 0 0 0 0 10 0 10 0 0 0 0 0 0 0 0 % N
% Pro: 10 10 0 10 0 37 0 0 0 0 0 0 0 0 0 % P
% Gln: 46 0 0 0 0 10 0 10 0 0 0 10 0 0 10 % Q
% Arg: 0 0 19 0 0 0 0 10 0 0 0 0 0 0 73 % R
% Ser: 0 0 10 0 10 28 55 55 0 37 0 0 10 0 0 % S
% Thr: 0 0 0 0 10 0 0 0 0 55 0 0 0 0 0 % T
% Val: 0 0 10 10 0 0 0 0 0 0 0 10 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 10 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _